Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ic50 for monomerid = 50015089
TargetLactoperoxidase(Bos taurus (Bovine))
University Of Otago Christchurch

LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  400nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
TargetThyroid peroxidase(Homo sapiens (Human))
University Of Otago Christchurch

LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  2.00E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human myeloperoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  5.93E+3nMAssay Description:Inhibition of recombinant Trypanosoma brucei brucei alternative oxidase using ubiquinol-1 as substrate incubated for 2 mins followed by substrate add...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquinol oxidase 1, mitochondrial(Voodoo lily)
Alternox Scientific

US Patent
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  7.00E+3nMAssay Description:Table 1 summarises the concentration of inhibitor required to reduce the respiration of purified recombinant AOX protein by 50%. Respiration was meas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMyeloperoxidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  2.50E+4nMpH: 6.5Assay Description:Assays were performed at 22 °C with 2 nM MPO and 10 μM hydrogen peroxide (H2O2) in 20 mM NaH2PO4 buffer, pH 6.5 containing 140 mM NaCl, 10 mM ta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  3.00E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)
Affinity DataIC50:  3.02E+4nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells(RBL-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed