TargetMembrane primary amine oxidase(Homo sapiens (Human))
Fi-40014 University Of Jyvaskyla
Curated by ChEMBL
Fi-40014 University Of Jyvaskyla
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human recombinant VAP-1 expressed in CHO cells after 30 mins by coupled colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro ability of the compound to inhibit Monoamine oxidase A activity in rat whole brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:In vitro ability of the compound to inhibit Monoamine oxidase B activity in rat whole brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: >8.97E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair