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Found 11 of ic50 for monomerid = 50183062
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of HO-1 in Sprague-Dawley albino rat spleen microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins...More data for this Ligand-Target Pair
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant truncated HO-1 (Met1 to Pro267) in rat spleen microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen HO1More data for this Ligand-Target Pair
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO1More data for this Ligand-Target Pair
TargetHeme oxygenase 1(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of HO1 in rat spleen microsomal fraction assessed as carbon monoxide productionMore data for this Ligand-Target Pair
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HO-2 in Sprague-Dawley albino rat brain microsomes assessed as reduction in bilirubin formation using hemin as substrate after 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeme oxygenase 2(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant truncated HO-2 (Met1 to Ala288) in rat brain microsomes expressed in Escherichia coli by spectrometry based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Queen'S University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  1.82E+5nMAssay Description:Inhibition of rat brain nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed