Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of ic50 for monomerid = 50229971
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  171nMAssay Description:Inhibition of human CK1D using KRRRAL[pS]VASLPGL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase II subunit alpha(Schizosaccharomyces pombe 972h-)
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Schizosaccharomyces pombe CK1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of GST-fused rat CK1delta expressed in Escherichia coli using phosphorylated peptide TFRPRTSpSNASTIS as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CK1delta in the presence of 100uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha/delta/epsilon/gamma-1/gamma-2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CK1 in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CK1deltaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
University Of Florida

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  338nMAssay Description:Inhibition of human CK1E using KRRRAL[pS]VASLPGL as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Rattus norvegicus (rat))
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  353nMAssay Description:Inhibition of rat CK1delta in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of ALK5Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of p38-alpha MAPK in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase D1(Homo sapiens (Human))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of PKD1 in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of GST-fused human p38alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50229971(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed