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Found 5 of ic50 for monomerid = 50231688
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231688(CHEMBL252458 | N-((2S,3R)-4-(2,6-dimethylheptan-2-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231688(CHEMBL252458 | N-((2S,3R)-4-(2,6-dimethylheptan-2-...)
Affinity DataIC50:  210nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 42 production by cell based assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231688(CHEMBL252458 | N-((2S,3R)-4-(2,6-dimethylheptan-2-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of BACE1 assessed as beta amyloid 40 production by cell based assayMore data for this Ligand-Target Pair
TargetCathepsin D(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231688(CHEMBL252458 | N-((2S,3R)-4-(2,6-dimethylheptan-2-...)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50231688(CHEMBL252458 | N-((2S,3R)-4-(2,6-dimethylheptan-2-...)
Affinity DataIC50:  5.89E+3nMAssay Description:Inhibition of BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed