Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for monomerid = 50248471
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50:  440nMAssay Description:Inhibition of human ERG by patch clamp techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50248471(1,1,1-trifluoro-2-(4-((R)-2-methyl-4-((1-(pyridin-...)
Affinity DataIC50:  440nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed