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Compile Data Set for Download or QSAR

Found 1 hit of ic50 for monomerid = 50251673   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
C5a anaphylatoxin chemotactic receptor (C5aR)


(Homo sapiens (Human))
BDBM50251673
PNG
((+/-)-N,2-bis(2,6-dimethylphenyl)-4-methoxy-N-meth...)
Show SMILES COc1cc(nc2CCCC(N(C)c3c(C)cccc3C)c12)-c1c(C)cccc1C
Show InChI InChI=1/C27H32N2O/c1-17-10-7-11-18(2)25(17)22-16-24(30-6)26-21(28-22)14-9-15-23(26)29(5)27-19(3)12-8-13-20(27)4/h7-8,10-13,16,23H,9,14-15H2,1-6H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay


Bioorg Med Chem Lett 18: 3852-5 (2008)


Article DOI: 10.1016/j.bmcl.2008.06.059
BindingDB Entry DOI: 10.7270/Q2765F4X
More data for this
Ligand-Target Pair