Compile Data Set for Download or QSAR
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Found 14 of ic50 for monomerid = 50252513
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Xinjiang Technical Institute Of Physics And Chemistry

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  5.20nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Xinjiang Technical Institute Of Physics And Chemistry

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  8.30nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) K1 cells stably expressing hERG measured using I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) measured using manual patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.26E+3nMAssay Description:Inhibition of rapid delayed inward rectifying potassium current (IKr) in Chinese hamster ovary (CHO) cells stable expressing hERG measured using IonW...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of fast sodium current (INa) in Chinese Hamster Ovary (CHO) K1 cells transfected with human Nav1.5 measured using IonWorks Quattro automat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  6.31E+4nMAssay Description:Inhibition of transient outward potassium current (Ito) current in Chinese Hamster Ovary (CHO) K1 cells expressing human Kv4.3 measured using IonWork...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.58E+5nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.94E+5nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  2.51E+5nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  3.98E+5nMAssay Description:Inhibition of fast sodium current (INa) in HEK293 cells transfected with human Nav1.5 measured using IonWorks Quattro automated patch clamp platformMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50252513(3-(2-(4-(6-fluorobenzo[d]isoxazol-3-yl)piperidin-1...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibition of slow delayed inward rectifying potassium current (Iks) in Chinese Hamster Ovary (CHO) cells expressing hKvLQT1/hminK measured using Ion...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed