Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 for monomerid = 50323813
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of G9a assessed as hydrolysis of S-adenosyl-L-homocysteine after 2 mins by SAHH-coupled fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  15nMAssay Description:Activity at methyl transferase activity GLP by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  23nMAssay Description:Activity at methyl transferase activity GLP by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of methyl transferase activity of G9a assessed as inhibition of H3K9 methylation by chemiluminescence based oxygen tunneling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Activity at methyl transferase activity G9a by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of G9a in human MDA-MB-231 cells assessed as reduction of H3K9me2 after 48 hrs by In-Cell Western assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 3 [N508S](Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Activity at methyl transferase activity PRMT3 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetN-lysine methyltransferase KMT5A(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Activity at methyl transferase activity SET8/preSet7 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50323813(7-(2-(2-(Dimethylamino)ethoxy)ethoxy)-6-methoxy-2-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Activity at methyl transferase activity SET7/9 by enzyme coupled S-adenocylehomocystein detection assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed