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Found 11 of ic50 for monomerid = 50389698
TargetCalcium/calmodulin dependent protein kinase with a kinas domain and 4 calmodulin-like EF hands(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1, putative(Cryptosporidium parvum (strain Iowa II))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  0.800nMAssay Description:Two types of enzyme assays were developed to follow TgCDPK1 activity, a radiometric scintillation proximity assay measured the labeled γ-phospha...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.30nMAssay Description:Most known kinase inhibitors bind in the ATP-binding pocket of the active site19,20. These inhibitors exploit many of the same hydrophobic contacts a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcGMP-dependent protein kinase()
University Of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphorimaging methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University Of Washington Through Its Center For

US Patent
LigandPNGBDBM50389698(CHEMBL2070065 | US10544104, Compound 37 | US112479...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In DepthDetails US Patent