Affinity DataKi: 0.220nMAssay Description:Inhibition of matrix metalloprotease-2 (MMP-2).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -54.0kJ/mole IC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Binding affinity for matrix metalloproteinase 13More data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Inhibition of matrix metalloprotease-13 (MMP-13).Checked by AuthorMore data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.550nMAssay Description:Inhibition of matrix metalloprotease-9More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 0.580nMAssay Description:Inhibition of matrix metalloprotease-9 (MMP-9).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by ChEMBL
Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of matrix metalloprotease-3 (MMP-3).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 17.5nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Inhibition of matrix metalloprotease-1 (MMP-1).Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 590nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
Affinity DataKi: 800nM ΔG°: -34.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of matrix metalloprotease-7 (MMP-7).Checked by AuthorMore data for this Ligand-Target Pair