Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ki for monomerid = 11876
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11876(1-(Cyclopropylmethyl)-N-hydroxy-4-[(4-phenoxypheny...)
Affinity DataKi: <0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11876(1-(Cyclopropylmethyl)-N-hydroxy-4-[(4-phenoxypheny...)
Affinity DataKi: <0.100nMAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM11876(1-(Cyclopropylmethyl)-N-hydroxy-4-[(4-phenoxypheny...)
Affinity DataKi:  770nM ΔG°:  -34.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibitors were assayed against purified hMMP-1, hMMP-2, hMMP-3, hMMP-8, hMMP-9, and hMMP-13 using an enzyme assay based on cleavage of the quenched ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed