BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 412953   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
G-protein coupled receptor 6


(Homo sapiens (Human))
BDBM412953
PNG
(US10406157, Compound Formula 1)
Show SMILES CC(=O)N1CCc2nc(N3CCC(CC3)Oc3ccc(F)cc3F)c(NC3CCOC3)nc2C1
Show InChI InChI=1S/C24H29F2N5O3/c1-15(32)31-10-6-20-21(13-31)28-23(27-17-7-11-33-14-17)24(29-20)30-8-4-18(5-9-30)34-22-3-2-16(25)12-19(22)26/h2-3,12,17-18H,4-11,13-14H2,1H3,(H,27,28)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
UniChem
US Patent
5.5n/an/an/an/an/an/an/an/a



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibition constant (Ki) from a GPR6 competition binding assay and the IC50 values from a hERG functional assay for the compound of Formula 1 (Ex...


US Patent US10406157 (2019)


BindingDB Entry DOI: 10.7270/Q2J105HQ
More data for this
Ligand-Target Pair