Affinity DataKi: 3.10nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of bovine hippocampus.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat hippocampal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Binding affinity to 5-HT1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]-8-OH-DAPT from human 5-HT1A receptor expressed in CHO-K1 cells membrane by scintillation counter analysisMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by microbeta2 sc...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor stably expressed in CHO-K1 cell membranes measured after 60 mins by Microbeta2 scintillation...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:5-HT1A: Radioligand binding was performed using membranes from CHO-K1 cells stably transfected with the human 5-HT1A receptor. All assays were carrie...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity was determined against 5-hydroxytryptamine 1A receptor using [3H]WB-4101More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by displacing [3H]WB-4101 from rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Ability to displace [3H]-DPAT from 5-hydroxytryptamine 1A receptor in homogenates of bovine hippocampus.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat hippocampal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 8.60nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT (0.5 nM) ligand in hippocampus + frontal bovine was determin...More data for this Ligand-Target Pair
Affinity DataKi: 8.90nMAssay Description:Agonist activity at 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 9.30nMAssay Description:Binding affinity against rat 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro inhibition of [3H]spiperone binding to 5-hydroxytryptamine 1A receptor from rat hippocampal tissue.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:In vitro ability to inhibit [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Antagonist activity against rat hippocampal tissue 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 12nM ΔG°: -45.2kJ/moleT: 2°CAssay Description:The composition of the assay buffers was as follows: for 5-HT1AR: 50 mM Tris¿HCl, 0.1 mM EDTA, 4 mM MgCl2, 10 lM pargyline, and 0.1% ascorbate; for 5...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 12.3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in the rat brain (hippocampus) using [3H]-8-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity against 5-hydroxytryptamine 1A receptor in rat cerebral cortical membrane using [3H]-8-OH-DPAT as radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity to D2 receptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]U-86170 from human D2-dopamine receptor expressed in CHO K1 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibitory affinity constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in CRL:CD(SD)BR-COBS rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity by measuring displacement of [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Binding affinity against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 15.4nMAssay Description:In vitro ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor sites of rat brain cortex.More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Affinity for 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Inhibition of [3H]5-HT binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in HEK293 cell membranes after 1 hr by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in human HEK293 cells assessed as inhibitory constant incubated for 1 hr by radioligand bi...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1AR in rat hippocampusMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 20nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 20.5nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Institute Of Pharmacology Of The Polish Academy Of Sciences
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Binding affinity at 5-hydroxytryptamine 1A receptor in rat cerebral cortex membranes by [3H]-8-OH-DPAT displacement.More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]5-carboxamidotryptamine to human 5HT1A expressed in HEK293 cells by filter binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in CHO-K1 cell membranes incubated for 60 mins by microbeta scintillation counting...More data for this Ligand-Target Pair