Affinity DataKi: 0nMAssay Description:Compound was measured for the inhibition of pepsin hydrolysis of hemoglobin.More data for this Ligand-Target Pair
Affinity DataKi: 0.0100nMAssay Description:Binding affinity against human cathepsin DChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 0.0560nMAssay Description:Inhibition of porcine pepsinMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Binding affinity to HIV-1 proteaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Inhibition of HIV-1 recombinant protease using DABCYL-GABA-Ser-Asn-Tyr-Pro-Ile-Val-Gln-EDANS as substrate incubated for 30 mins prior to substrate ad...More data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of HIV1 protease by Lineweaver-Burke methodMore data for this Ligand-Target Pair
Affinity DataKi: 38nMAssay Description:Inhibition of HIV1 protease by Hanes methodMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Inhibition of HIV1 protease by Dixon methodMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Inhibition of HIV-1 recombinant protease using DABCYL-GABA-Ser-Asn-Tyr-Pro-Ile-Val-Gln-EDANS as substrate incubated for 30 mins prior to substrate ad...More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Inhibition of HIV-1 recombinant protease using DABCYL-GABA-Ser-Asn-Tyr-Pro-Ile-Val-Gln-EDANS as substrate incubated for 30 mins prior to substrate ad...More data for this Ligand-Target Pair
Affinity DataKi: 94nMAssay Description:Inhibition of wild-type HIV-1 protease using fluorogenic peptide substrate incubated for 30 mins prior to substrate addition measured after 10 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Antihypertensive activity against human reninMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Inhibition of multidrug resistant HIV-1 protease L10I/L63P/A71V/G73S/I84V/L90M mutant using fluorogenic peptide substrate incubated for 30 mins prior...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coliMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:The compound was tested for its affinity against HIV-1 protease; range 400-1400 nMMore data for this Ligand-Target Pair
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Agouron Pharmaceuticals
Agouron Pharmaceuticals
Affinity DataKi: 3.10E+3nM ΔG°: -32.7kJ/molepH: 5.5 T: 2°CAssay Description:Protease activity was measured by continuous chromogenic assay. The chromogenic peptide His-Lys-Ala-Arg-Val-Leu- (p-NO2-Phe)-Glu-Ala-Nleu-Ser (Bache...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of ReninMore data for this Ligand-Target Pair
TargetGag-Pro polyprotein(Human T-cell leukemia virus 1 (strain Japan ATK-1 ...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 1.46E+4nMAssay Description:Inhibitory binding affinity towards recombinant human T-cell leukemia virus type I (HTLV-1) proteaseMore data for this Ligand-Target Pair
TargetGag-Pro polyprotein(Human T-cell leukemia virus 1 (strain Japan ATK-1 ...)
Kyoto Pharmaceutical University
Curated by ChEMBL
Kyoto Pharmaceutical University
Curated by ChEMBL
Affinity DataKi: 3.65E+4nMAssay Description:Inhibitory binding affinity towards synthesized human T-cell leukemia virus type I (HTLV-1) proteaseMore data for this Ligand-Target Pair