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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '1,5-anhydro-D-fructose reductase' and Ligand = 'BDBM269306'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
1,5-anhydro-D-fructose reductase


(Homo sapiens (Human))
BDBM269306
PNG
((R)-2-(4-(benzo[d]oxazol-2-yl)-2-fluorophenyl)-1-(...)
Show SMILES CC1(C)N=C(N(C[C@@H]2CCN(C2)C(=O)C2CC2)C1=O)c1ccc(cc1F)-c1nc2ccccc2o1
Show InChI InChI=1S/C27H27FN4O3/c1-27(2)26(34)32(15-16-11-12-31(14-16)25(33)17-7-8-17)23(30-27)19-10-9-18(13-20(19)28)24-29-21-5-3-4-6-22(21)35-24/h3-6,9-10,13,16-17H,7-8,11-12,14-15H2,1-2H3/t16-/m1/s1
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 437n/an/an/an/a7.525



Janssen Pharmaceutica NV

US Patent


Assay Description
10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...


US Patent US9718813 (2017)

More data for this
Ligand-Target Pair