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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '1,5-anhydro-D-fructose reductase' and Ligand = 'BDBM269334'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
1,5-anhydro-D-fructose reductase


(Homo sapiens (Human))
BDBM269334
PNG
(2-(2-fluoro-4-(6-fluoronaphthalen-2-yl)phenyl)-1-(...)
Show SMILES CC1(C)N=C(N(CC2CN(C2)C(=O)C2(O)CC2)C1=O)c1ccc(cc1F)-c1ccc2cc(F)ccc2c1
Show InChI InChI=1S/C29H27F2N3O3/c1-28(2)26(35)34(16-17-14-33(15-17)27(36)29(37)9-10-29)25(32-28)23-8-6-21(13-24(23)31)18-3-4-20-12-22(30)7-5-19(20)11-18/h3-8,11-13,17,37H,9-10,14-16H2,1-2H3
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 120n/an/an/an/a7.525



Janssen Pharmaceutica NV

US Patent


Assay Description
10 μL assay buffer (100 mM KH2PO4 pH 7.5) was added to a 384-well clear plate (costar 3702). 0.3 μL compound (at concentrations of 30 μ...


US Patent US9718813 (2017)

More data for this
Ligand-Target Pair