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Found 2 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50080412'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50080412(CHEMBL3422266)
Affinity DataIC50:  76nMAssay Description:Inhibition of human 11beta-HSD1 overexpressed in microsomal fraction of HEK293 cells assessed as formation of [3H]-cortisol from [3H]-cortisone by sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50080412(CHEMBL3422266)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of mouse 11beta-HSD1 overexpressed in microsomal fraction of HEK293 cells assessed as formation of [3H]-cortisol from [3H]-cortisone by sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed