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Found 3 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50112126'
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112126(CHEMBL3608406 | US9464044, 74)
Affinity DataIC50:  2.60nMpH: 6.0 T: 2°CAssay Description:The inhibiting activity of 11β-HSD1 derived from microsomal fractions was measured using the HTRF assay (62CO2PEB, Cisbio). Different concentrat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Incheon National University

Curated by ChEMBL
LigandPNGBDBM50112126(CHEMBL3608406 | US9464044, 74)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Ahn-Gook Pharmaceutical

US Patent
LigandPNGBDBM50112126(CHEMBL3608406 | US9464044, 74)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed