Found 7 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50248569'
Affinity DataKi: 1.10nMAssay Description:Inhibition of human 11beta-HSD1 using variable cofactor NADPH concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Inhibition of human 11beta-HSD1 using variable substrate cortisol concentration by Lineweaver burk plotMore data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in baculovirus insect cell system assessed as conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
Affinity DataIC50: 0.830nMAssay Description:Inhibition of human 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of FLAG tagged human recombinant 11beta-HSD1 reductase activity expressed in Trichoplusia ni Hi5 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human 11beta-HSD1 transfected in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair