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Found 1 hit Enz. Inhib. hit(s) with Target = '15-Lipoxygenase-2 (15-LOX-2)' and Ligand = 'BDBM50011735'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
15-Lipoxygenase-2 (15-LOX-2)


(Homo sapiens (Human))
BDBM50011735
PNG
(CHEMBL3262908)
Show SMILES CNc1oc(nc1C#N)-c1cccc(Cl)c1Cl
Show InChI InChI=1S/C11H7Cl2N3O/c1-15-11-8(5-14)16-10(17-11)6-3-2-4-7(12)9(6)13/h2-4,15H,1H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged human epithelial 15-lipoxygenase-2 using arachidonic acid as substrate by UV-vis spectrometric analysis


J Med Chem 57: 4035-48 (2014)


Article DOI: 10.1021/jm401915r
BindingDB Entry DOI: 10.7270/Q26T0P58
More data for this
Ligand-Target Pair