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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '15-Lipoxygenase-2 (15-LOX-2)' and Ligand = 'BDBM56150'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
15-Lipoxygenase-2 (15-LOX-2)


(Homo sapiens (Human))
BDBM56150
PNG
((6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyr...)
Show SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C
Show InChI InChI=1S/C17H16N2O/c1-11-7-8-17(20)14(9-11)16-10-15(18-19-16)13-6-4-3-5-12(13)2/h3-10,20H,1-2H3,(H,18,19)
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Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of N-terminal His6-tagged human 15-LOX-2 using arachidonic acid as substrate by UV-visible spectrophotometric analysis


Bioorg Med Chem 24: 1183-90 (2016)


Article DOI: 10.1016/j.bmc.2016.01.042
BindingDB Entry DOI: 10.7270/Q2QJ7K44
More data for this
Ligand-Target Pair