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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide dependent protein kinase-1' and Ligand = 'BDBM50321379'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-phosphoinositide dependent protein kinase-1


(Homo sapiens (human))
BDBM50321379
PNG
(4-(1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-b...)
Show SMILES OC(=O)CN1c2ccccc2CCC(Sc2ccc(cc2)C(O)=O)C1=O
Show InChI InChI=1S/C19H17NO5S/c21-17(22)11-20-15-4-2-1-3-12(15)7-10-16(18(20)23)26-14-8-5-13(6-9-14)19(24)25/h1-6,8-9,16H,7,10-11H2,(H,21,22)(H,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1.87E+5n/an/an/an/a



Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL


Assay Description
Displacement of PIFtide from His-tagged PDK1 by HTRF assay


Bioorg Med Chem Lett 20: 3897-902 (2010)


Article DOI: 10.1016/j.bmcl.2010.05.019
BindingDB Entry DOI: 10.7270/Q2Z60Q1H
More data for this
Ligand-Target Pair