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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 (51-359)' and Ligand = 'BDBM281803'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3-phosphoinositide-dependent protein kinase 1 (51-359)


(Homo sapiens (Human))
BDBM281803
PNG
((S)-N-(1-(3,4-difluorophenyl)ethyl)- 2-(((5-(1-met...)
Show SMILES C[C@H](NC(=O)c1cccnc1NCc1ccc(s1)-c1ccc2ncc3ncn(C)c3c2c1)c1ccc(F)c(F)c1
Show InChI InChI=1S/C30H24F2N6OS/c1-17(18-5-8-23(31)24(32)13-18)37-30(39)21-4-3-11-33-29(21)35-14-20-7-10-27(40-20)19-6-9-25-22(12-19)28-26(15-34-25)36-16-38(28)2/h3-13,15-17H,14H2,1-2H3,(H,33,35)(H,37,39)/t17-/m0/s1
PDB

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<100n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.; Millenium Pharmaceuticals, Inc.

US Patent


Assay Description
PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...


US Patent US10030016 (2018)

More data for this
Ligand-Target Pair