BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '3C-like proteinase (3CL-PRO)' and Ligand = 'BDBM50297252'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
3C-like proteinase (3CL-PRO)


(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
BDBM50297252
PNG
(7-(4-Chloro-benzyloxy)-2-(3,4-dihydroxy-phenyl)-3,...)
Show SMILES Oc1ccc(cc1O)-c1oc2cc(OCc3ccc(Cl)cc3)cc(O)c2c(=O)c1O
Show InChI InChI=1S/C22H15ClO7/c23-13-4-1-11(2-5-13)10-29-14-8-17(26)19-18(9-14)30-22(21(28)20(19)27)12-3-6-15(24)16(25)7-12/h1-9,24-26,28H,10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.10E+3n/an/an/an/an/an/a



Konkuk University

Curated by ChEMBL


Assay Description
Inhibition of SARS coronavirus helicase assessed as duplex-DNA unwinding by FRET based assay


Bioorg Med Chem Lett 19: 4538-41 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.009
BindingDB Entry DOI: 10.7270/Q2H41RGD
More data for this
Ligand-Target Pair
3C-like proteinase (3CL-PRO)


(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
BDBM50297252
PNG
(7-(4-Chloro-benzyloxy)-2-(3,4-dihydroxy-phenyl)-3,...)
Show SMILES Oc1ccc(cc1O)-c1oc2cc(OCc3ccc(Cl)cc3)cc(O)c2c(=O)c1O
Show InChI InChI=1S/C22H15ClO7/c23-13-4-1-11(2-5-13)10-29-14-8-17(26)19-18(9-14)30-22(21(28)20(19)27)12-3-6-15(24)16(25)7-12/h1-9,24-26,28H,10H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.09E+4n/an/an/an/an/an/a



Konkuk University

Curated by ChEMBL


Assay Description
Inhibition of ATPase activity of SARS coronavirus helicase assessed as phosphate release by malachite green assay


Bioorg Med Chem Lett 19: 4538-41 (2009)


Article DOI: 10.1016/j.bmcl.2009.07.009
BindingDB Entry DOI: 10.7270/Q2H41RGD
More data for this
Ligand-Target Pair