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Found 3 Enz. Inhib. hit(s) with Target = '5'-nucleotidase' and Ligand = 'BDBM419939'
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419939(US10472364, Compound 24 | US11208414, Cpd. # 24)
Affinity DataIC50:  5.90E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419939(US10472364, Compound 24 | US11208414, Cpd. # 24)
Affinity DataIC50:  5.90E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419939(US10472364, Compound 24 | US11208414, Cpd. # 24)
Affinity DataIC50:  1.64E+4nMAssay Description:The ability of compounds to inhibit endogenous, cell-bound CD73 enzyme activity was demonstrated using SK-MEL-28 cells, which express CD73 on their s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent