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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-Hydroxytryptamine receptor 6 (5-HT6)' and Ligand = 'BDBM50156209'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-Hydroxytryptamine receptor 6 (5-HT6)


(Homo sapiens (Human))
BDBM50156209
PNG
(CHEMBL3780579)
Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)NCC(C)(C)c1cccc2ccc(Br)cc12
Show InChI InChI=1S/C26H32BrN3O3S/c1-26(2,23-7-5-6-19-8-9-20(27)16-22(19)23)18-28-34(31,32)21-10-11-25(33-4)24(17-21)30-14-12-29(3)13-15-30/h5-11,16-17,28H,12-15,18H2,1-4H3
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 0.310n/an/an/an/an/an/a



Temple University

Curated by ChEMBL


Assay Description
Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO cell membranes after 120 mins by liquid scintillation counting method


ACS Med Chem Lett 7: 12-4 (2016)


Article DOI: 10.1021/acsmedchemlett.5b00466
BindingDB Entry DOI: 10.7270/Q2Z89F8F
More data for this
Ligand-Target Pair