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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A (5-HT1A)' and Ligand = 'BDBM319690'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1A (5-HT1A)


(Homo sapiens (human))
BDBM319690
PNG
(7-(2-(4-(thieno[2,3-c]pyridin-4-yl)piperazin-1-yl)...)
Show SMILES O=c1ccc2ccc(CCN3CCN(CC3)c3cncc4sccc34)cc2[nH]1
Show InChI InChI=1S/C22H22N4OS/c27-22-4-3-17-2-1-16(13-19(17)24-22)5-7-25-8-10-26(11-9-25)20-14-23-15-21-18(20)6-12-28-21/h1-4,6,12-15H,5,7-11H2,(H,24,27)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 1.23n/an/an/an/a



SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES; SUZHOU VIGONVITA LIFE SCIENCES CO., LTD.; TOPHARMAN SHANDONG CO., LTD.

US Patent


Assay Description
The 5-HT1A receptor agonism activity test (The agonism activity of test compounds on 5-HT1A receptor expressing human recombinant 5-HT1A receptor in ...


US Patent US10174011 (2019)

More data for this
Ligand-Target Pair