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Found 4 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1B' and Ligand = 'BDBM50033383'
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKi:  4.20nMAssay Description:In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataIC50:  6.20nMAssay Description:Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataEC50:  16nMAssay Description:Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Centre De Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  1.5nMAssay Description:Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank