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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1B' and Ligand = 'BDBM50074163'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))
BDBM50074163
PNG
(3-(2-Azetidin-1-yl-ethyl)-5-[1,2,4]triazol-4-yl-1H...)
Show SMILES C(Cc1c[nH]c2ccc(cc12)-n1cnnc1)N1CCC1
Show InChI InChI=1S/C15H17N5/c1-5-19(6-1)7-4-12-9-16-15-3-2-13(8-14(12)15)20-10-17-18-11-20/h2-3,8-11,16H,1,4-7H2
PDB

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PC cid
PC sid
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Patents


Similars

Article
PubMed
n/an/a 4.40n/an/an/an/an/an/a



Merck, Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT binding from the cloned human 5-hydroxytryptamine 1B receptor stably expressed in CHO cells


J Med Chem 42: 677-90 (1999)


Article DOI: 10.1021/jm9805687
BindingDB Entry DOI: 10.7270/Q23777W5
More data for this
Ligand-Target Pair