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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1B' and Ligand = 'BDBM50083105'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 1B


(Homo sapiens (Human))
BDBM50083105
PNG
(CHEMBL358072 | Pyridin-2-yl-{1-[3-(5-[1,2,4]triazo...)
Show SMILES C(CN1CCC(CNc2ccccn2)CC1)Cc1c[nH]c2ccc(cc12)-n1cnnc1
Show InChI InChI=1S/C24H29N7/c1-2-10-25-24(5-1)27-15-19-8-12-30(13-9-19)11-3-4-20-16-26-23-7-6-21(14-22(20)23)31-17-28-29-18-31/h1-2,5-7,10,14,16-19,26H,3-4,8-9,11-13,15H2,(H,25,27)
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Similars

Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-5-HT binding to cloned 5-hydroxytryptamine 1B receptor stably expressed in CHO cells


J Med Chem 42: 4981-5001 (2000)


Article DOI: 10.1021/jm9910021
BindingDB Entry DOI: 10.7270/Q20P0Z77
More data for this
Ligand-Target Pair