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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50231452'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-hydroxytryptamine receptor 2A


(Homo sapiens (human))
BDBM50231452
PNG
(CHEMBL253439 | N-(6-(2-(4-(benzo[d]isothiazol-3-yl...)
Show SMILES Clc1ccc(cc1)C(=O)NC1CCc2ccc(CCN3CCN(CC3)c3nsc4ccccc34)cc12
Show InChI InChI=1S/C29H29ClN4OS/c30-23-10-7-22(8-11-23)29(35)31-26-12-9-21-6-5-20(19-25(21)26)13-14-33-15-17-34(18-16-33)28-24-3-1-2-4-27(24)36-32-28/h1-8,10-11,19,26H,9,12-18H2,(H,31,35)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
0.100n/an/an/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from human 5HT2A receptor expressed in Swiss 3T3 cells


Bioorg Med Chem Lett 18: 489-93 (2008)


Article DOI: 10.1016/j.bmcl.2007.11.106
BindingDB Entry DOI: 10.7270/Q2611023
More data for this
Ligand-Target Pair