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Found 2 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B' and Ligand = 'BDBM50249173'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249173((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(py...)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50249173((4-(1H-benzo[d]imidazol-2-yl)piperidin-1-yl)(4-(py...)
Affinity DataIC50:  1.70E+3nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) expressed in CHOK1 cells assessed as inhibition of serotonin-induced intracellular Ca2+ flux ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed