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Found 4 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50171264'
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50171264(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Affinity DataKi:  82nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50171264(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Affinity DataKi:  84nMAssay Description:Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Organix

Curated by ChEMBL
LigandPNGBDBM50171264(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Affinity DataKi:  359nMAssay Description:Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSOMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Organix

Curated by ChEMBL
LigandPNGBDBM50171264(CHEMBL197646 | US11427604, Compound (I-43) | US115...)
Affinity DataEC50:  99nMAssay Description:Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed