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Found 3 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM166225'
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM166225(US9067949, 81a | US9067949, 82a | US9067949, 82b)
Affinity DataKi:  0.150nM ΔG°:  -56.1kJ/molepH: 7.5 T: 2°CAssay Description:For binding analysis vs. the human receptor, samples were incubated in 50 mM Tris-HCl, pH 7.5, 5 mM MgCl2, 1 mM EDTA (4% DMSO final) with 10 nM [N-me...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM166225(US9067949, 81a | US9067949, 82a | US9067949, 82b)
Affinity DataKi:  0.350nM ΔG°:  -54.0kJ/molepH: 7.5 T: 2°CAssay Description:For binding analysis vs. the human receptor, samples were incubated in 50 mM Tris-HCl, pH 7.5, 5 mM MgCl2, 1 mM EDTA (4% DMSO final) with 10 nM [N-me...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Albany Molecular Research

US Patent
LigandPNGBDBM166225(US9067949, 81a | US9067949, 82a | US9067949, 82b)
Affinity DataKi:  56nM ΔG°:  -41.4kJ/molepH: 7.5 T: 2°CAssay Description:For binding analysis vs. the human receptor, samples were incubated in 50 mM Tris-HCl, pH 7.5, 5 mM MgCl2, 1 mM EDTA (4% DMSO final) with 10 nM [N-me...More data for this Ligand-Target Pair
In DepthDetails US Patent