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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)' and Ligand = 'BDBM200924'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3)


(Homo sapiens (Human))
BDBM200924
PNG
(US9233946, 23)
Show SMILES Fc1cc(F)cc(c1)-c1ccc(s1)S(=O)(=O)Nc1cccc(c1)-c1nnn[nH]1
Show InChI InChI=1S/C17H11F2N5O2S2/c18-12-6-11(7-13(19)9-12)15-4-5-16(27-15)28(25,26)22-14-3-1-2-10(8-14)17-20-23-24-21-17/h1-9,22H,(H,20,21,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 620n/an/an/an/an/an/a



KANCERA AB

US Patent


Assay Description
Method B: The kinase activity of the bi-functional enzyme is readily quantified based on the production of ADP and F-2,6-P2 from ATP and F6P. The ADP...


US Patent US9233946 (2016)


BindingDB Entry DOI: 10.7270/Q2V123KB
More data for this
Ligand-Target Pair