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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM196870'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ALK tyrosine kinase receptor


(Homo sapiens (Human))
BDBM196870
PNG
(US9212192, 33)
Show SMILES COc1cc(ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2ccnc2c1C(N)=O)C(=O)NCCN1CCCCC1
Show InChI InChI=1S/C29H31Cl2N7O3/c1-41-23-16-18(29(40)34-10-14-37-12-3-2-4-13-37)8-9-22(23)35-27-25(26(32)39)28-33-11-15-38(28)24(36-27)17-19-20(30)6-5-7-21(19)31/h5-9,11,15-16,35H,2-4,10,12-14,17H2,1H3,(H2,32,39)(H,34,40)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
1 -51.4n/an/an/an/an/a7.425



AbbVie Inc.

US Patent


Assay Description
ALK kinase assays were conducted with the indicated final concentrations unless otherwise specified. In 384 well black plates (Axygen), 8 ul of compo...


US Patent US9212192 (2015)


BindingDB Entry DOI: 10.7270/Q2D79971
More data for this
Ligand-Target Pair