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Found 2 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50193823'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50193823(CHEMBL3934268)
Affinity DataIC50:  2nMAssay Description:Inhibition of human ALK expressed in baculovirus using recombinant GST PLC-gamma as substrate assessed as phosphorylation of the substrate after 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50193823(CHEMBL3934268)
Affinity DataIC50:  30nMAssay Description:Inhibition of NPM-ALK phosphorylation in human SUP-M2 cells after 2 to 3 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed