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Found 2 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50382653'
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50382653(CHEMBL2023996)
Affinity DataIC50:  60nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620) expressed in SF9 cells using Biotin-Ahx- EQEDEPEGIYGVLF-OH as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50382653(CHEMBL2023996)
Affinity DataIC50:  61nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed