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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK2' and Ligand = 'BDBM50056683'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ALK2


(Mus musculus)
BDBM50056683
PNG
(CHEMBL3341795)
Show SMILES COc1cc(OC)cc(c1)-c1cncc(c1)-c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C23H25N3O2/c1-27-22-12-18(13-23(14-22)28-2)20-11-19(15-25-16-20)17-3-5-21(6-4-17)26-9-7-24-8-10-26/h3-6,11-16,24H,7-10H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 260n/an/an/an/an/an/a



Massachusetts Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assay


J Med Chem 57: 7900-15 (2014)


Article DOI: 10.1021/jm501177w
BindingDB Entry DOI: 10.7270/Q2PK0HS6
More data for this
Ligand-Target Pair