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Found 1 hit Enz. Inhib. hit(s) with Target = 'AP-4-A phosphorylase' and Ligand = 'BDBM65563'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP-4-A phosphorylase


()
BDBM65563
PNG
(Synthesized Sulfanylacrylonitril Derivatives 10)
Show SMILES CCCS\C(Nc1cccc(c1)C(F)(F)F)=C(\C#N)S(=O)(=O)c1ccccc1
Show InChI InChI=1S/C19H17F3N2O2S2/c1-2-11-27-18(24-15-8-6-7-14(12-15)19(20,21)22)17(13-23)28(25,26)16-9-4-3-5-10-16/h3-10,12,24H,2,11H2,1H3/b18-17-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 470n/an/an/an/a8.0n/a



University of Konstanz



Assay Description
Dose response curves against Rv2613c with 1 as the substrate for derivatives 5 and 18. 8 nM of Rv2613c were preincubated in buffer (20 mM Tris-HCl (p...


ACS Chem Biol 12: 2682-2689 (2017)


Article DOI: 10.1021/acschembio.7b00653
BindingDB Entry DOI: 10.7270/Q2CV4FW6
More data for this
Ligand-Target Pair