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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM311287'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311287
PNG
((S)-1-((2′-chloro-4-(difluoromethyl)-5′...)
Show SMILES CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1cc(Cl)ncc1F
Show InChI InChI=1S/C18H21ClF3N3O/c1-10(2)6-18(3,23)9-26-15-8-24-14(4-12(15)17(21)22)11-5-16(19)25-7-13(11)20/h4-5,7-8,10,17H,6,9,23H2,1-3H3/t18-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.450n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US10155760 (2018)

More data for this
Ligand-Target Pair