BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM311362'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens (Human))
BDBM311362
PNG
((S)-2,4-dimethyl-1-((5-(quinolin-4-yl)-3-(trifluor...)
Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)(F)F)-c1ccnc2ccccc12
Show InChI InChI=1S/C22H24F3N3O/c1-14(2)11-21(3,26)13-29-20-18(22(23,24)25)10-15(12-28-20)16-8-9-27-19-7-5-4-6-17(16)19/h4-10,12,14H,11,13,26H2,1-3H3/t21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.590n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US10155760 (2018)

More data for this
Ligand-Target Pair