BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1 (AAK1)' and Ligand = 'BDBM335620'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1 (AAK1)


(Homo sapiens (Human))
BDBM335620
PNG
(N-(3-(2-isopropyl-2H-tetrazol-5-yl)phenyl)-5-((met...)
Show SMILES CNCc1ccn2ncnc(Nc3cccc(c3)-c3nnn(n3)C(C)C)c12
Show InChI InChI=1S/C18H21N9/c1-12(2)27-24-17(23-25-27)13-5-4-6-15(9-13)22-18-16-14(10-19-3)7-8-26(16)21-11-20-18/h4-9,11-12,19H,10H2,1-3H3,(H,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US9737542 (2017)

More data for this
Ligand-Target Pair