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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1 (AAK1)' and Ligand = 'BDBM335626'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1 (AAK1)


(Homo sapiens (Human))
BDBM335626
PNG
(5-((4-aminopiperidin-1-yl)methyl)-7-bromo-N-(3-(ox...)
Show SMILES NC1CCN(Cc2cc(Br)n3ncnc(Nc4cccc(c4)-c4cnco4)c23)CC1
Show InChI InChI=1S/C21H22BrN7O/c22-19-9-15(11-28-6-4-16(23)5-7-28)20-21(25-12-26-29(19)20)27-17-3-1-2-14(8-17)18-10-24-13-30-18/h1-3,8-10,12-13,16H,4-7,11,23H2,(H,25,26,27)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 3.00E+4n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US9737542 (2017)

More data for this
Ligand-Target Pair