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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1 (AAK1)' and Ligand = 'BDBM335652'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1 (AAK1)


(Homo sapiens (Human))
BDBM335652
PNG
(N-(3-(5-isopropyl-1,2,4-oxadiazol-3-yl)-5-methoxyp...)
Show SMILES COc1cc(Nc2ncnn3ccc(C)c23)cc(c1)-c1noc(n1)C(C)C
Show InChI InChI=1S/C19H20N6O2/c1-11(2)19-23-17(24-27-19)13-7-14(9-15(8-13)26-4)22-18-16-12(3)5-6-25(16)21-10-20-18/h5-11H,1-4H3,(H,20,21,22)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.17E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US9737542 (2017)

More data for this
Ligand-Target Pair