BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1 (AAK1)' and Ligand = 'BDBM335667'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1 (AAK1)


(Homo sapiens (Human))
BDBM335667
PNG
(N-(cyanomethyl)-4-((3-(2-isopropyl-2H-tetrazol-5-y...)
Show SMILES CC(C)n1nnc(n1)-c1cccc(Nc2ncnn3ccc(C(=O)NCC#N)c23)c1
Show InChI InChI=1S/C19H18N10O/c1-12(2)29-26-17(25-27-29)13-4-3-5-14(10-13)24-18-16-15(19(30)21-8-7-20)6-9-28(16)23-11-22-18/h3-6,9-12H,8H2,1-2H3,(H,21,30)(H,22,23,24)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 469n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US9737542 (2017)

More data for this
Ligand-Target Pair