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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP Phosphoribosyltransferase' and Ligand = 'BDBM25314'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP Phosphoribosyltransferase


(Mycobacterium tuberculosis)
BDBM25314
PNG
(2-[(5,6-diphenyl-1,2,4-triazin-3-yl)sulfanyl]-N-(1...)
Show SMILES O=C(CSc1nnc(-c2ccccc2)c(n1)-c1ccccc1)Nc1nccs1
Show InChI InChI=1S/C20H15N5OS2/c26-16(22-19-21-11-12-27-19)13-28-20-23-17(14-7-3-1-4-8-14)18(24-25-20)15-9-5-2-6-10-15/h1-12H,13H2,(H,21,22,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/a 4.00E+3n/an/an/an/a8.522



Yale University



Assay Description
Inhibition activity was determined using an assay that followed the production of PR-ATP spectrophotometrically. Enzymatic reaction was initiated by ...


J Med Chem 51: 5984-92 (2008)

More data for this
Ligand-Target Pair