Found 5 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM408663' TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 18.7nMAssay Description:human ROMK and rat ROMK: 1. Materials and Instruments (1) FluxOR potassium ion channel assay (F10016, Invitrogen) (2) Ouabain (03125-1G, Sigma)...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 40nMAssay Description:human ROMK and rat ROMK: 1. Materials and Instruments (1) FluxOR potassium ion channel assay (F10016, Invitrogen) (2) Ouabain (03125-1G, Sigma)...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 40nMAssay Description:The Inhibitory Activity of the Present Compounds on Human ROMK and Rat ROMK ChannelsThe method described hereafter was used for determining the inhib...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 192nMAssay Description:The Inhibitory Activity of the Present Compounds on Human ROMK and Rat ROMK ChannelsThe method described hereafter was used for determining the inhib...More data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
Jiangsu Hengrui Medicine
US Patent
Jiangsu Hengrui Medicine
US Patent
Affinity DataIC50: 192nMAssay Description:human ROMK and rat ROMK: 1. Materials and Instruments (1) FluxOR potassium ion channel assay (F10016, Invitrogen) (2) Ouabain (03125-1G, Sigma)...More data for this Ligand-Target Pair
