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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM50056512'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Activin receptor type-1


(Homo sapiens (Human))
BDBM50056512
PNG
(CHEMBL3341949)
Show SMILES Nc1ncc(cc1-c1ccc2OCCOc2c1)-c1ccc(cc1)N1CCNCC1
Show InChI InChI=1S/C23H24N4O2/c24-23-20(17-3-6-21-22(14-17)29-12-11-28-21)13-18(15-26-23)16-1-4-19(5-2-16)27-9-7-25-8-10-27/h1-6,13-15,25H,7-12H2,(H2,24,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.87E+3n/an/an/an/an/an/a



Massachusetts Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]


J Med Chem 57: 7900-15 (2014)


Article DOI: 10.1021/jm501177w
BindingDB Entry DOI: 10.7270/Q2PK0HS6
More data for this
Ligand-Target Pair